CHONDREX Arthrogen-CIA 5-Clone Cocktail Kit – 40mg

Collagen Antibody-Induced Arthritis (CAIA) has been generally utilized starting around 1998 when 4-clone mixed drink (Arthrogen-CIA arthritogenic monoclonal antibodies) units originally showed up.

To actuate steady joint inflammation all the more successfully in different mouse strains including CAIA low responder C57BL/6 mice, and an assortment of unusual knockout and transgenic mice with C57BL/6 (H-2b) or 129/Sv (H-2b) foundations, another 5-clone mixed drink units have been created by adding another clone to the 4-clone mixed drink.

The new 5-Clone CIAA creates quicker results: Typically serious joint pain is incited inside 24-48 hours rather than the a month expected to initiate CIA after inoculation with type II collagen. Not at all like the first CIA model, which requires a confined MHC haplotype, the new 5-Clone CAIA model is extensively pertinent and can prompt joint pain in practically all kinds of mice, including CIA-safe, T-cell lacking, quality knockout, and transgenic mice.

Usefully the new 5-Clone units offer phenomenal consistency meaning the seriousness of joint inflammation incited now straightforwardly connects to the portion of monoclonal immune response mixed drink, and more extreme and reliable joint inflammation can be prompted by expanding the portion of monoclonal counter acting agent mixed drink.

Hence, this model is great for concentrating on the neurotic job of individual quality items, cytokines, as well as screening and assessing mitigating specialists without impacts of complete or deficient Freund’s adjuvant, which emphatically influences the host’s resistant framework.

Established in 1987, AMS Biotechnology (AMSBIO) is perceived today as a main organization adding to the speed increase of disclosure through the arrangement of state of the art life science innovation items and administrations for innovative work in the clinical, nourishment, beauty care products and energy businesses.

The AMSBIO range incorporates expert antibodies, peptides and recombinant proteins. Likewise the organization can draw upon top to bottom mastery in extracellular lattices to give exquisite answers for concentrating on cell motility, relocation, intrusion and expansion.

Generally recognized as specialists in cell culture, AMSBIO accomplices with clients in fitting cell frameworks to improve screening results and inevitable guess. With a scope of atomic identification reagents, and a huge Biorepository the organization can likewise give tissue DNA, RNA, protein and microarray items.
Creature models have added to amazing advances in the comprehension of various human sicknesses. As important
as creature models are, a few disadvantages do exist. One such disadvantage originates from the various wellsprings of changeability which
can influence the result of the examinations.

In this manner, a pilot study is by and large suggested for first time clients of all creature models. A concise conversation of the 2 central matters of changeability will be made sense of underneath.

1. Mouse Vendors

The hereditary foundation of mice, even in a similar strain, will fluctuate from one merchant to another and can influence how the creatures
answer different reagents, along these lines affecting the consequences of your analysis (1). Along these lines, testing creatures from various
merchants utilizing a characterized convention is suggested prior to continuing with an enormous full-scale analyze.

2. Lodging Conditions

The microorganisms greenery is vital to the strength of the creature, including the legitimate working of the safe framework (1).
Subsequently, we suggest lodging creatures in Specific Pathogen Free (SPF) conditions instead of regular circumstances
to stay away from fluctuation brought about by microorganisms.
In general, exceptional thought of these primary concerns of fluctuation will help the analyst in finishing their trials with
less jumbling results.

CAIA sidesteps the prerequisite for host’s age of autoantibodies to type II collagen, consequently can be initiated in mice that try not to have CIA-helpless MHC-haplotypes (H-2q and H-2r) like different knockout or transgenic mice.

All kinds of mice, which are typical regarding mounting a provocative reaction including supplement enactment, ought to be
defenseless to CAIA.

Arthrogen-CIA 5-Clone Cocktail Kit - 10mg

53010 Chondrex 10 mg/ml x 1 ml 720 EUR

Arthrogen-CIA 5-Clone Cocktail Kit - 40mg

53040 Chondrex 10 mg/ml x 4 ml 2781 EUR

Arthrogen-CIA 5-Clone Cocktail Kit - 100mg

53100 Chondrex 10 mg/ml x 10 ml 6695 EUR

Rabbit Anti Human FOXO1 Monoclonal Clone CIA-6

IRBAHUFOXO1CIA6C100UL Innovative research each 496 EUR

MHC Class II (I-A) mouse monoclonal antibody, clone CIa-I, PE

AM08124RP-N Origene Technologies GmbH 100 µg Ask for price

MHC Class II (I-A) mouse monoclonal antibody, clone CIa-I, FITC

AM08124FC-N Origene Technologies GmbH 500 µg Ask for price

MHC Class II (I-A) mouse monoclonal antibody, clone CIa-I, Biotin

AM08124BT-N Origene Technologies GmbH 500 µg Ask for price

MHC Class II (I-A) mouse monoclonal antibody, clone CIa-I, Purified

AM08124PU-N Origene Technologies GmbH 500 µg Ask for price

Monoclonal CIAS1 Antibody (monoclonal) (M01), Clone: 3B1

AMM03391G Leading Biology 0.1mg 580.8 EUR

Monoclonal CIAPIN1 Antibody (monoclonal) (M01), Clone: 5G8

AMM03390G Leading Biology 0.1mg 580.8 EUR

Monoclonal GFAP Antibody (clone GA-5), Clone: GA-5

APG03319G Leading Biology 0.05mg 580.8 EUR

Monoclonal NKX2-5 Antibody (monoclonal) (M01), Clone: S3

AMM06706G Leading Biology 0.1mg 580.8 EUR

Monoclonal NKX2-5 Antibody (monoclonal) (M02), Clone: S1

AMM06707G Leading Biology 0.1mg 580.8 EUR

Monoclonal CCL5 / RANTES Antibody (clone 50013-5), Clone: 50013-5

AMM02131G Leading Biology 0.05ml 580.8 EUR

Monoclonal ART3 Antibody (clone 3A2), Clone: 3A2

AMM01902G Leading Biology 0.05mg 633.6 EUR

Monoclonal FTO Antibody (clone 5-2H10), Clone: 5-2H10

AMM04626G Leading Biology 0.05ml 580.8 EUR

Monoclonal Antibody to 5-Lipoxygenase (5-LO)

MAB355Hu21 Cloud-Clone 100ul 246 EUR

Monoclonal Antibody to 5-Lipoxygenase (5-LO)

MAB355Hu22 Cloud-Clone 100ul 246 EUR

Monoclonal Antibody to 5-Lipoxygenase (5-LO)

MAB355Hu23 Cloud-Clone 100ul 253 EUR

Monoclonal Antibody to 5-Lipoxygenase (5-LO)

MAB355Hu24 Cloud-Clone 100ul 250 EUR

Monoclonal ARTS-1 Antibody (monoclonal) (M01), Clone: 4H8

AMM03275G Leading Biology 0.1mg 580.8 EUR

Artn mouse monoclonal antibody, clone 185230

MO15021-500 Origene Technologies GmbH 500 µg Ask for price

Monoclonal Antibody to Cadherin 5 (CDH5)

MAB366Hu22 Cloud-Clone 100ul 203 EUR

Monoclonal Antibody to Cadherin 5 (CDH5)

MAB366Ra21 Cloud-Clone 100ul 267 EUR

Monoclonal Antibody to Cadherin 5 (CDH5)

MAB366Ra22 Cloud-Clone 100ul 271 EUR

Monoclonal Antibody to Cadherin 5 (CDH5)

MAB366Ra23 Cloud-Clone 100ul 272 EUR

Monoclonal Antibody to Interleukin 5 (IL5)

MAA078Bo21 Cloud-Clone 100ul 279 EUR

Monoclonal Antibody to Interleukin 5 (IL5)

MAA078Hu21 Cloud-Clone 100ul 252 EUR

Monoclonal Antibody to Interleukin 5 (IL5)

MAA078Hu22 Cloud-Clone 100ul 235 EUR

Monoclonal Antibody to Interleukin 5 (IL5)

MAA078Po21 Cloud-Clone 100ul 279 EUR

Monoclonal Antibody to Interleukin 5 (IL5)

MAA078Po22 Cloud-Clone 100ul 288 EUR

Keratin 5 (KRT5) Monoclonal Antibody (Human)

4-MAA488Hu22 Cloud-Clone
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  • 100ul
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Monoclonal CD59 Antibody (clone MEM-43/5), Clone: MEM-43/5

AMM01725G Leading Biology 0.05mg 580.8 EUR

Nephritogenic Monoclonal Antibody, Clone 114, 5 mg

70205 Chondrex 1 mg/ml x 5 ml 3502 EUR

Interleukin 5 (IL5) Monoclonal Antibody (Human)

4-MAA078Hu22 Cloud-Clone
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  • 100ul
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Mfn2 mouse monoclonal antibody, clone N153/5

75-173 Origene Technologies GmbH 100 µl Ask for price

PHYH mouse monoclonal antibody, clone N210/5

75-238 Origene Technologies GmbH 100 µl Ask for price

Kcna4 mouse monoclonal antibody, clone L71/5

75-316 Origene Technologies GmbH 100 µl Ask for price

CD40 mouse monoclonal antibody, clone G28-5

DDX0130P-100 Origene Technologies GmbH 100 µg Ask for price

Mfn2 mouse monoclonal antibody, clone N153/5

73-173 Origene Technologies GmbH 5 ml Ask for price

PHYH mouse monoclonal antibody, clone N210/5

73-238 Origene Technologies GmbH 5 ml Ask for price

Kcna4 mouse monoclonal antibody, clone L71/5

73-316 Origene Technologies GmbH 5 ml Ask for price

RBM17 mouse monoclonal antibody, clone N219/5

75-234 Origene Technologies GmbH 100 µl Ask for price

Cadm4 mouse monoclonal antibody, clone N244/5

75-247 Origene Technologies GmbH 100 µl Ask for price

CLCN3 mouse monoclonal antibody, clone N258/5

75-259 Origene Technologies GmbH 100 µl Ask for price

RBM17 mouse monoclonal antibody, clone N219/5

73-234 Origene Technologies GmbH 5 ml Ask for price

Cadm4 mouse monoclonal antibody, clone N244/5

73-247 Origene Technologies GmbH 5 ml Ask for price

CLCN3 mouse monoclonal antibody, clone N258/5

73-259 Origene Technologies GmbH 5 ml Ask for price

CIAPIN1 mouse monoclonal antibody,clone OTI1A2

TA808781 Origene Technologies GmbH 100 µl Ask for price

CIAPIN1 mouse monoclonal antibody,clone OTI1A2

TA808781S Origene Technologies GmbH 30 µl Ask for price

Monoclonal CD11c FITC Monoclonal Antibody (Clone 3.9), Clone: 3.9

APR15331G Leading Biology 50 tests 580.8 EUR

Keratin 5 (KRT5) Monoclonal Antibody (Human), PE

4-MAA488Hu22-PE Cloud-Clone
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Keratin 5 (KRT5) Monoclonal Antibody (Human), APC

4-MAA488Hu22-APC Cloud-Clone
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  • 100ul
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Keratin 5 (KRT5) Monoclonal Antibody (Human), Cy3

4-MAA488Hu22-Cy3 Cloud-Clone
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Keratin 5 (KRT5) Monoclonal Antibody (Human), HRP

4-MAA488Hu22-HRP Cloud-Clone
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  • 100ul
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Keratin 5 (KRT5) Monoclonal Antibody (Human), FITC

4-MAA488Hu22-FITC Cloud-Clone
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Monoclonal STX5 / Syntaxin 5 Antibody (clone 5A6), Clone: 5A6

AMM08041G Leading Biology 0.05mg 633.6 EUR

Monoclonal CD28 FITC Monoclonal Antibody (Clone CD28.2), Clone: CD28.2

AMM00025G Leading Biology 0.05mg 475.2 EUR

Cd4 rat monoclonal antibody, clone RM4-5, PE

AM05638RP-N Origene Technologies GmbH 1 ml/100 Tests Ask for price

Interleukin 5 (IL5) Monoclonal Antibody (Human), PE

4-MAA078Hu22-PE Cloud-Clone
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  • 100ul
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Monoclonal Cytokeratin 5 Antibody, Clone: 1E1

AMM05823G Leading Biology 0.1ml 580.8 EUR

Interleukin 5 (IL5) Monoclonal Antibody (Human), APC

4-MAA078Hu22-APC Cloud-Clone
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  • 100ul
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Interleukin 5 (IL5) Monoclonal Antibody (Human), Cy3

4-MAA078Hu22-Cy3 Cloud-Clone
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  • 100ul
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Interleukin 5 (IL5) Monoclonal Antibody (Human), HRP

4-MAA078Hu22-HRP Cloud-Clone
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Monoclonal Antibody to Interferon Alpha 5 (IFNa5)

MAG975Hu22 Cloud-Clone 100ul 196 EUR

Monoclonal LRP-5/6 Antibody (Clone 1A12)

APR08268G Leading Biology 0.1mg 633.6 EUR

Monoclonal CD63 Antibody (clone AHN16.1/46-4-5), Clone: AHN16.1/46-4-5

AMM02309G Leading Biology 0.05mg 580.8 EUR

Kallikrein 5 (KLK5) mouse monoclonal antibody, clone 193318

MO15028-500 Origene Technologies GmbH 500 µg Ask for price

Nephritogenic Monoclonal Antibody, Clone a84, 5 mg

70215 Chondrex 1 mg/ml x 5 ml 3502 EUR

Nephritogenic Monoclonal Antibody, Clone b35, 5 mg

70225 Chondrex 1 mg/ml x 5 ml 3502 EUR

Interleukin 5 (IL5) Monoclonal Antibody (Human), FITC

4-MAA078Hu22-FITC Cloud-Clone
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  • 100ul
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5'-Nucleotidase, Ecto (NT5E) Monoclonal Antibody (Rat)

4-MAB250Ra21 Cloud-Clone
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  • 100ul
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Cd38 rat monoclonal antibody, clone NIMR-5, PE

AM08041RP-N Origene Technologies GmbH 200 µg Ask for price

Cd38 rat monoclonal antibody, clone NIMR-5, PE

AM08041RP-S Origene Technologies GmbH 100 µg Ask for price

Cd4 rat monoclonal antibody, clone RM4-5, FITC

AM05638FC-N Origene Technologies GmbH 100 µg Ask for price

Monoclonal Cytokeratin 5 Antibody, Clone: 3E2F1

APR15660G Leading Biology 0.1ml 633.6 EUR

5'-Nucleotidase, Ecto (NT5E) Monoclonal Antibody (Human)

4-MAB250Hu21 Cloud-Clone
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  • 100ul
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Interferon Alpha 5 (IFNa5) Monoclonal Antibody (Human)

4-MAG975Hu22 Cloud-Clone
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  • 100ul
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Cd38 rat monoclonal antibody, clone NIMR-5, APC

AM08041AC-N Origene Technologies GmbH 100 µg Ask for price

CD38 mouse monoclonal antibody, clone AT13/5, PE

SM1106R Origene Technologies GmbH 100 Tests Ask for price

CD38 mouse monoclonal antibody, clone AT13/5, PE

SM1106RT Origene Technologies GmbH 25 Tests Ask for price

Monoclonal Antibody to Mucin 5 Subtype B (MUC5B)

MAA684Hu21 Cloud-Clone 100ul 243 EUR

Monoclonal Antibody to Mucin 5 Subtype B (MUC5B)

MAA684Hu22 Cloud-Clone 100ul 235 EUR

Monoclonal Antibody to Mucin 5 Subtype B (MUC5B)

MAA684Hu23 Cloud-Clone 100ul 243 EUR

Monoclonal Antibody to Mucin 5 Subtype B (MUC5B)

MAA684Hu24 Cloud-Clone 100ul 243 EUR

Monoclonal Antibody to Mucin 5 Subtype B (MUC5B)

MAA684Hu25 Cloud-Clone 100ul 243 EUR

Nonetheless, it is far-fetched that Only autoantibodies are fit for instigating immune system infections in people. For instance, microbes poisons, for example, lipopolysaccharide (LPS), Staphylococcal enterotoxin B (SEB), and M. arthritidis mitogen (MAM), play a synergistic impact with autoantibodies to type II collagen, and instigates serious joint inflammation in mice.

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